Interaction of Fe(III) haem with antimalarials and effects on haem in cultured parasites. Speciation and behaviour of free Fe(III) haem in aqueous solution. Biomimetic investigations of β-haematin (synthetic haemozoin/malaria pigment) formation.
Research interests: understanding how the malaria parasite deals with the large influx of haem associated with ingestion and degradation of haemoglobin in its digestive vacuole and the effects of antimalarials such as chloroquine, which inhibit this process. PhD (Bioinorganic Chemistry), Head of Department and Jamison Professor of Inorganic Chemistry, Science Faculty, UCT. His work is funded by the SA MRC, SA NRF, EU FP7, EDCTP and NIH. His group’s main research interests are the study of pulmonary regulatory immunological pathways in relation to infection, rapid and field-friendly diagnosis of tuberculosis, and drug-resistant tuberculosis.
He holds an honorary faculty position at UCL. Keertan Dheda (MBBCh (Wits), FCP (SA), FCCP, PhD (Lond)) is Head of the Lung Infection and Immunity Unit and Associate Professor of Respiratory Medicine (SARChI), Division of Pulmonology and UCT Lung Institute, Department of Medicine, University of Cape Town. Research interests: HIV cohort and infectious disease epidemiology operations research on service responses for priority health conditions data harmonisation and linkage and context-appropriate health information systems development.
Division of Public Health Medicine and Centre for Infectious Disease Epidemiology and Research (CIDER), School of Public Health and Family Medicine Wellcome Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Institute of Infectious Disease and Molecular Medicine Health Impact Assessment directorate, Department of Health, Provincial Government of the Western Cape. Affiliate membership is for researchers based at UCT, elsewhere than in the IDM complex, who seek supplementary membership of the IDM because their research interests align with the general focus and current activity areas of the IDM, for 3-year terms, which are renewable.
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